About
Scientifically trained life-science executive with extensive leadership experience in drug discovery and development, business development and licensing, corporate management, fund-raising and shareholder relations.
Experience
Operating Partner
Present
Mission BioCapital brings together two U.S.-based early-stage life science venture funds: BioInnovation Capital and Mission Bay Capital. As Operating Partner, I work closely with some exceptionally talented young management teams for MBC's portfolio companies. Currently I am Executive Chairman for Mitokinin Therapeutics, Telo Therapeutics, Epiodyne, and ARase Therapeutics.
Director
Senior Advisor
Deciphera Pharmaceuticals, Inc. · Waltham, Massachusetts
President & Ceo
Deciphera Pharmaceuticals, Inc. · Waltham, Massachusetts
Deciphera Pharmaceuticals is a clinical-stage biopharmaceutical company focused on improving the lives of cancer patients by tackling key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off” or inactivated conformation. These investigational therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candida…
President & Ceo
Ensemble Therapeutics Corp.
CEO of groundbreaking Drug Discovery Company developing a novel class of therapeutics. Completed 7 Research Alliances with Major Pharma partners. Co-inventor of first-in-class small molecule inhibitors of IL-17, an important clinically-validated autoimmune modulator.
Director
Marina Biotech
Served as Independent Director of this public company, including Audit, Compensation and Nominating Committees.
Senior Vice President
2000-2006 Global Head, project and portfolio management 2006-2007 Investor Development & Strategy
Drug Development Vice President
Led preclinical through late-stage development teams in oncology, cardiovascular, and neurology including Lipitor, Caduet, Neurontin, conivaptan, Onyx-015, suramin and SNX-111 during development, registration, and/or post-launch stages.
Drug Development Vp
Parke-Davis Pharmaceutical Research
Led preclinical through late-stage development teams in oncology, cardiovascular, and neurology including Lipitor, Caduet, Neurontin, conivaptan, Onyx-015, suramin and SNX-111 during development, registration, and/or post-launch stages.
Education
University of Pennsylvania
Post-Doc, Organic Chemistry
University at Buffalo
Ph.D., Medicinal Chemistry
University of South Florida
B.S., Chemistry
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