How to Run an Email Campaign Targeting Shopify Plus Merchants Hiring a Head of Ecommerce (2026)

You’ve already built a high‑intent list of Shopify Plus merchants actively hiring a Head of Ecommerce using Origami — now comes the part that actually books meetings: the email campaign. Origami isn’t just a list builder; it has a built‑in email sequencer that handles the full outreach flow, from finding leads to sending multi‑touch sequences and tracking replies, all inside one platform. You don’t need to export CSVs, sync with a separate tool, or pay for a standalone email sender. That matters because a well‑crafted 3‑touch sequence sent to the right people at the right time can convert at 5–12%, and you’re about to see exactly how to set it up.

If you haven’t built the list yet, stop here and read how to build a list of Shopify Plus Merchants Hiring a Head of Ecommerce first. That guide shows you the exact prompt to run inside Origami (and yes, you can do it on the free plan — 1,000 credits, no credit card required). Once you have 50–200 qualified leads in your dashboard, come back and turn them into conversations.

Step 1: Refine and segment your list before you send a single email

Origami returns verified names, work emails, job titles, company details, and usually enriched signals like tech stack and recent news. Right out of the prompt you’ll have a clean list. But blasting the whole list with the same message is a mistake. A Head of Ecommerce at a $5M brand has different priorities than one at a $100M brand. Spend 15 minutes segmenting and you’ll add 2–5 points to your reply rate.

Inside Origami’s list view, you can filter and tag leads using the enriched fields. I segment every campaign into three buckets:

• Urgency — Filter by when the job posting was detected (Origami often shows the “first seen” date). Leads with a listing under 14 days old get “Hot” tag; 15–30 days “Warm”. Hot leads are far more likely to reply because the company is still actively screening candidates.
• Company revenue or employee count — If your product solves a problem that emerges above $20M in revenue (complex inventory, multi‑warehouse fulfillment), cut anything below $10M. Conversely, if you sell a lightweight tool, lean into mid‑market. Origami enriches firmographics, so use the “revenue” filter to build sub‑lists.
• Role specifics — Sometimes a title says “Head of Ecommerce & Digital Growth” vs plain “Head of Ecommerce”. The first often owns P&L and will care about revenue impact. The second might be more operations‑focused. Tag them so your message hooks hit the right pain.

What “qualified” means for this audience — A qualified lead is a Shopify Plus merchant with a role live in the last 30 days, matching your ICP revenue band, and ideally showing a signal of tech complexity (e.g., they already use ShipStation, NetSuite, or a WMS). If you’re selling an inventory forecasting tool, the sweet spot is $15M–$200M brands running multiple sales channels. If you’re selling on‑site personalization, you might target the high‑SKU apparel segment. The key: your segmentation creates a small set of micro‑segments you can write one slightly tailored template for, even if you use the AI writer later.

Clean the list by removing any duplicate domains (the same company hiring for multiple roles is fine, but you only need one contact — usually the CEO or VP of People if the Head role isn’t filled yet). Origami already deduplicates by email, but check for company overlap manually if you scraped from multiple sources.

Step 2: Write — or let Origami write — a 3‑touch email sequence that feels custom

Origami gives you two paths:

1. Paste your own templates — You write a 3‑touch sequence inside the sequencer builder, set delays between touches (Day 1, Day 3, Day 7 — or whatever cadence you want), and hit “Launch”. You can add personalization tokens like {first_name}, {company}, {title} directly in the text, just like any ESP.
2. Let the agent write it — Instead of copying and pasting, you can ask the Origami AI agent to generate a personalized 3‑day email sequence for all your leads automatically. The agent reads each lead’s profile — title, company, industry, tools — and writes messages that reference their specific situation. It writes different copy for the $10M apparel brand versus the $80M home goods brand, without you doing manual segment work.

Below I’m giving you a sequence you can copy‑paste and adapt for manual sending, but if you decide to let the agent write it, use this same structure as a prompt template: “Write a 3‑touch email sequence for Shopify Plus merchants hiring a Head of Ecommerce, focusing on helping the new hire automate inventory forecasting and reduce stockouts. Reference their company and role. Keep each email under 100 words. Use delays Day 1, Day 3, Day 7.”

Full 3‑touch sequence you can steal today

Assume you sell an inventory optimization platform (say, “StockPulse”) that helps multi‑channel Shopify Plus brands predict demand and automate purchase orders. Every message targets the pain of the soon‑to‑be‑hired Head of Ecommerce inheriting messy inventory.

Touch 1 – Initial cold email (Day 1)

Subject: Your new Head of Ecommerce hire
Preview text: A quick idea to short‑circuit their first 90 days

{first_name}, just saw your listing for a Head of Ecommerce — congrats on the growth. When that person starts, they’ll face bloated inventory costs, overselling across channels, and spreadsheets that lie.

StockPulse automates demand forecasting and multi‑channel syncing for Shopify Plus brands, cutting stockouts by 30% and freeing their first 60 days for strategy instead of firefighting.

Want to see if it fits the 90‑day plan? Open to a quick call next week.

Touch 2 – Follow‑up, different angle (Day 3)

Subject: The 90‑day playbook high‑performing e‑commerce leaders steal
Preview text: Something we mapped out across 200+ Shopify Plus brands

{first_name}, after working with dozens of Heads of Ecommerce on Shopify Plus, a pattern emerged: the ones who hit revenue targets in Q1 always automated forecasting first. The ones who didn’t fought spreadsheets and still ran out of stock.

Our platform gives your incoming lead a clean predictive dashboard and cross‑channel alerts in 48 hours — with zero dev work.

Can I send our free “First 90 Days” checklist? 200+ brands used it to set up their e‑com team fast. No pitch, just the PDF.

Touch 3 – Final breakup (Day 7)

Subject: Quick close on {company}’s e‑commerce hire
Preview text: No hard feelings either way

{first_name}, I’ll be brief. I know your main focus is finding the right leader. If smarter inventory isn’t a priority for the new Head of Ecommerce right now, I won’t keep pinging you.

Just leaving this: Shopify Plus brands using StockPulse typically see a 15% lift in full‑price sell‑through within 60 days. Anytime it matters, I’m around. Otherwise, I’ll leave you alone.

These three messages are all 50–100 words, direct, and avoid fluff. If you’re selling a different product — say, fraud protection or site search — swap the pain point but keep the structure: (1) trigger on the hire, (2) a proven pattern or playbook, (3) a gracious exit that leaves a concrete metric. The agent path will adapt this logic automatically.

Step 3: Launch the campaign directly from Origami — no exporting, no syncing

Here’s where Origami changes the game. After you’ve refined your list and set up the sequence (whether manually pasted or agent‑written), you launch it right from the same dashboard. There’s no need to export contacts to a separate email tool or CRM. Everything stays inside the platform.

How to send:

• Select the contact list you built and refined.
• Click “Create sequence” (inside the sequencer tab).
• Choose your cadence — I use Day 1, Day 3, Day 7, but you can set any intervals.
• Attach the 3 messages. If you use the agent, it will pre‑fill the sequence with personalized emails per lead; if you paste templates, you’ll use the same copy for all, with token personalization.
• Hit “Launch” and the sequencer starts sending at the predefined times.

What you see after launch:

• Opens, clicks, replies — All tracked in a single live dashboard, per contact.
• Prospect context remains visible — While checking a contact’s activity, you still see their enriched profile (title, company, tools used, job posting date). So when someone opens three times but hasn’t replied, you know it’s a $12M brand using ShipStation and can send a manual follow‑up with a relevant case study.
• Automatic un‑enrollment — If a lead replies (even “not interested”), they immediately leave the active sequence. You never send a breakup message after someone books a meeting.

What it costs: Origami’s email sequencer is included on all paid plans. You only pay for credits to enrich leads (and the free 1,000 credits cover your first test). There’s no extra fee to send sequences. Paid plans start at $29/month. This means you can build a list for a few hundred leads, run a full campaign, and only pay for the enrichment credits you consume — sending is free.

What response rate to expect and how to iterate

For a curated list of Shopify Plus merchants with a confirmed open Head of Ecommerce role, expect a reply rate between 5% and 12% on the first campaign, depending on how tight your segmentation is and how relevant the sequence feels.

• If you’re below 4% replies, your list likely has weak intent — maybe the roles were scraped from stale sources, or the companies aren’t truly Shopify Plus (but Shopify Advanced instead). Re‑run the enrichment in Origami with tighter filters or a fresh prompt.
• If opens are healthy (40%+) but replies are low, the messaging is off. Try a different hook in Touch 1, like leading with a specific operational metric they’re losing (e.g., “average Shopify Plus brand loses 6% of revenue to avoidable stockouts”). Origami’s AI can quickly generate variant sequences if you ask it to swap the angle.
• A reply like “we already filled this role” still counts as a signal — update your list so you can reach out with a different play three months later when the new hire is settled.

Iterate in 50‑lead batches. Pause the sequence after 50 sends, review reply quality, and tune before scaling to the full list.