Quick answer: To run a cold email campaign that Medical Directors in New York actually read, first source a verified list from Origami. Then, qualify every contact against clinical-decision authority. Use the exact 3‑touch sequence below — written for their real pain points: readmission penalties, NYS Medicaid metrics, and patient flow — and send it using Origami’s built-in email sequencer (free on all paid plans). Expect a 2–5% positive reply rate. Below I walk you through the whole process, step by step.

I’ve run dozens of these campaigns selling into New York health systems. Medical Directors are not your typical executive buyer. Their inbox is a warzone of vendor pitches, JCAHO notices, and COVID‑variant updates. To cut through, you need a list that’s surgically precise, a message that lands on their operational stress, and a light cadence that respects their time. This post is the companion to my earlier guide how to build a list of Medical Directors in New York — over there I covered sourcing the names. Here, I’m giving you the campaign. And now that Origami includes a built-in sequencer, you can manage the entire process — from list to sent — without ever leaving the platform.

Step 1: Build the List in Origami

Even if you already ran this step, a quick recap helps. In Origami, you type one prompt and the AI agent builds the list from the live web, enriches the contacts, and hands you a spreadsheet. Here’s the exact prompt I used last week for a patient‑throughput solution:

Prompt: Medical Directors in New York City metropolitan area, currently practicing in acute-care hospitals or large multi‑specialty groups, with verified work email and direct phone.

Origami returns a targeted prospect list with:

Full name, MD suffix, clinical title (e.g., Medical Director, Emergency Services)
Hospital name, address, bed count, health system affiliation
Verified direct email and often a mobile number
LinkedIn profile URL and any recent publications or news mentions

The free plan gives you 1,000 credits — enough for several hundred contacts — no credit card required. Paid plans start at $29/month. Every email I got was catch‑all checked and SMTP‑verified, so bounce rates stayed below 2% on my sends.

Step 2: Refine and Qualify the List

A raw list of “Medical Directors in NY” still contains misfires. I take the Origami export and trim it with these rules:

Remove Bad Fits

Academic directors without clinical operations authority. If their title is “Medical Director of Education” or “Program Director, Residency” and they don’t manage a clinical service line, they’re not buyers.
Administrative-only roles. “Medical Director of Utilization Review” might influence but rarely has a budget. Save them for a later nurture track.
Pediatric‑only directors if you’re selling an adult‑medicine solution, and vice versa.
Locums or interim titles. These folks rotate out in 3 months.

Segment by Company Size & Role

Split the list into two buckets:

Large health system (500+ beds) – e.g., NYU Langone, Mount Sinai, Northwell, NewYork‑Presbyterian. These Medical Directors have ownership of a clinical service line, a dedicated budget, and pressure from a CMO to hit quality metrics. They’ll care about enterprise‑wide solutions: patient flow platforms, staffing optimization tools, or clinical decision support that integrates with Epic.
Community hospitals & large multi‑specialty groups – 100‑400 beds, often in boroughs outside Manhattan or upstate suburbs. These Directors are closer to the day‑to‑day, sometimes still practicing. They react to acute issues like ED overcrowding, nurse staffing ratios, or compliance with NYS Department of Health mandates on readmissions.

What “Qualified” Looks Like for Medical Directors

A qualified contact:

Holds an active New York medical license (I spot‑check a few on the NYSED license verification site)
Has direct reports or service‑line P&L responsibility (visible from org charts or LinkedIn)
Works in a facility that publicly reports CMS readmission or HCAHPS scores — meaning they are measured
Shows “signals”: recent leadership move, hospital expansion, or a new quality initiative mentioned in press releases

If I have a list of 300 names from Origami, I’ll typically qualify down to 80‑120 that fit a tight ICP. Then I bucket them into sequences.

Step 3: Write and Set Up the Email Sequence

When you’re ready to sequence, Origami gives you two ways to build your outreach:

Paste your own templates: Write your own multi-touch sequence (like the 3‑step one below), copy the templates into Origami’s sequencer, set delays between touches (Day 1, Day 3, Day 7, or whatever cadence fits), and hit “Launch.”
Let the AI agent write it: Ask Origami’s AI agent to generate a personalized multi-day email sequence for all your qualified leads automatically. The agent crafts each message based on each lead’s profile data — title, company, industry — so every message feels custom. It’s a huge time-saver, and you still review and tweak before sending.

Below is the exact 3‑touch sequence I used last quarter for a patient discharge planning tool. The product doesn’t matter; the pains do. Steal this copy and adapt your value proposition.

All messages are between 50‑100 words. I use plain text, no images, so they look like an internal memo.

Touch 1 — Day 1: Initial Cold Email

Subject: reducing LOS at ? Preview: Readmissions under 10% aren’t the norm in Brooklyn

Hi ,

I saw reports a CMS readmission rate near 16% for CHF patients — pretty common for large NYC facilities, but you know VBP penalties add up.

We help medical directors at Northwell and Montefiore cut post‑discharge bounce‑backs by 30% in 90 days without adding headcount.

Worth 15 minutes to see how they’re doing it?

Best,

Touch 2 — Day 3: Follow‑up (Different Angle)

Subject: NY Medicaid’s 30‑day metric Preview: Many NYC hospitals missed the target last year

NYS’s Medicaid Redesign Team just tightened the 30‑day all‑cause readmission threshold. A few of your peers are using automated post‑discharge navigation to keep patients connected to PCP follow‑ups within 7 days — no extra staff.

I put a 2‑pager together on how medical directors are hitting the metric. I can shoot it over — just let me know if I have the right person.

Touch 3 — Day 7: Breakup Email

Subject: Closing out for now — discharge workflows Preview: One last thought on patient throughput

I know you’re buried. I’ll leave you with this: if the ADT feed in your ED was surfacing real‑time risk scores, how much would that move the needle on your LOS dashboard?

If that project ever becomes a priority, my door’s open. If you’re not the one looking at throughput, could you point me to the right director?

Thanks,

Why this sequence works for Medical Directors in New York:

Touch 1 calls out a specific metric (CHF readmissions) and local peers (Northwell, Montefiore). Medical Directors benchmark against each other.
Touch 2 references a New York‑specific regulation — the Medicaid Redesign Team changes are real. This signals you understand the regulatory pressure.
Touch 3 is simple, no‑pitch, and asks an operational question. Even if they aren’t in buying mode, they might forward it to the nursing director or quality lead — expanding your pool.

A few customization notes:

If you’re selling to medical directors at community hospitals, swap the peer orgs for ones in the same region (e.g., “St. Joseph’s in Yonkers” or “Wyckoff Heights Medical Center”).
If your solution is clinical supply chain or capital equipment, pivot the pain to “OR turnover time” or “capital spend vs. value‑based budgets.”

Step 4: Launch, Send, and Track — All Inside Origami

Once your sequence is set up (whether you pasted your own or had the agent build it), you’ll launch it straight from Origami’s built-in sequencer. There’s no exporting to a separate tool, no syncing, no extra cost for the sequencing engine.

Here’s how the sending and tracking works:

Configure delays: Set the gaps between emails — I use Day 1, Day 3, and Day 7, but you can choose any interval.
One-click launch: After you hit “Launch,” Origami sends the multi-step sequence automatically from your connected mailbox. Each lead receives the first touch, then the follow-ups based on your timing.
Track opens, clicks, replies: The same dashboard where you refined your list now shows real-time engagement. You’ll see who opened, who clicked, who replied — no juggling platforms.
Full prospect context: Click on any lead’s activity and you’ll see their enriched profile right there: hospital, title, recent news, contact details. So you never lose context between list building and outreach.
Auto un-enrollment: If a Medical Director replies to any touch, they automatically exit the sequence. No more “got your email, but you kept emailing me” awkwardness.

The best part? The sequencer is included in all paid Origami plans (starting at $29/month) and doesn’t consume extra credits. You only pay for the enrichment credits used to build your list. You can even start with the free 1,000 credits to test the entire flow — build a list, qualify, sequence, and see results before committing. It’s truly a find‑enrich‑sequence‑send‑track machine in one platform.

After your first run, revisit the dashboard. Identify who opened but didn’t reply — you might retarget them with a different angle later. And if a lead replies asking to be removed, Origami handles that gracefully, keeping your sender reputation safe.

Put it all together, and you have a repeatable, scalable workflow that respects a Medical Director’s time while getting you meetings.

Rotate Your Device

How to Run an Email Campaign Targeting Medical Directors in New York in 2026