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How to Run an Email Campaign to Companies Hiring AI Product Managers & Heads of AI (2026)

Step-by-step guide to sending a 3-touch cold email sequence to companies hiring AI Product Managers and Heads of AI using Origami's built-in sequencer — from list refinement to launch.

Charlie Mallery
Charlie MalleryUpdated 11 min read

GTM @ Origami

Quick Answer: Once you've built a list of companies hiring AI Product Managers or Heads of AI using Origami (covered in our parent guide), you don't export to another tool. Origami has a built-in email sequencer — you can refine that list, craft a 3‑touch cold email sequence tailored to each company’s exact hiring context, and launch the campaign from the same dashboard where you found the leads. No CSV exports, no separate sending platform. Below I’ll walk through the exact workflow, including a ready‑to‑steal 3‑touch sequence for this audience.


Step 1 — Build the List in Origami (Recap)

If you’ve already built your list, skip to Step 2. If not, here’s the one‑prompt start that feeds the campaign.

In Origami’s search bar, type:

Find US-based companies that currently have open roles for "AI Product Manager" or "Head of AI", with at least 20 employees and raised Series A or later. Include the hiring manager’s name, email, and LinkedIn.

Origami’s AI agent scours live job boards, company career pages, LinkedIn, and data partners. In minutes you get a cleaned, enriched prospect table with:

  • Company name, size, industry, funding stage, tech stack
  • Job title, posting date, seniority level
  • Verified contact name, email, and phone for the person likely to own that hire — often a VP Product, CTO, or Head of Talent

You can do this on the free plan (1,000 enrichment credits, no credit card) to test the list quality before upgrading.


Step 2 — Refine and Qualify the List

A raw list of 300 companies with open AI product roles is not a campaign. You need to sharpen it until you have 50–80 accounts you’d genuinely want to work with and where the contact has both budget and urgency.

How to review the list in Origami

Open the Leads tab. Use the built‑in filters to:

  • Remove recently filled roles: Sort by “Posting date” and drop any job posted more than 60 days ago — the odds of it still being open are much lower.
  • Filter by company size: For AI Product Manager roles, stick to 50–1,000 employees. Smaller than 50 might have an improv‑hire process; larger than 1,000 often have rigid recruiting stacks that are harder to displace.
  • Filter by funding: Series A, B, or growth‑stage companies. They have the cash to invest in AI leadership and the pressure to move fast.
  • Location focus: If your solution works best in North America or certain time zones, trim the list to 1‑2 geos.

What “qualified” looks like for this audience

A qualified account meets all these traits:

  1. The AI PM or Head of AI role is still open (LinkedIn or company site confirms it).
  2. The contact you’re emailing is the direct hiring authority — the person this role would report to, or a senior talent partner embedded in the tech org.
  3. The company has recently invested in AI (product announcements, new AI org, or a C‑suite AI hire). That tells you they’ll pay for speed and quality.
  4. The contact’s email is verified and not a generic careers@ inbox.

Tap the “Qualified” toggle on each lead. Export the qualified segment into a new list so you’re not wasting sequences on mismatches.


Step 3 — Create the Email Sequence

Origami’s sequencer gives you two paths, and both live right inside the same product where your list sits.

Option 1 — Paste your own templates

You write a 3‑touch sequence (like the one below), paste each message into the sequence builder, set the delays (e.g., Day 1, Day 3, Day 7), and hit “Launch.” You can use merge fields like , , or `` and the sequencer fills them in automatically.

Option 2 — Let the agent write it

If you’d rather not stare at a blank cursor, ask Origami’s AI agent to generate a personalized 3‑day email sequence for your list. It reads each lead’s profile — title, company, industry, recent tech stack additions — and creates messages that feel individually written. You can always edit the generated texts before sending.

Complete 3‑Touch Sequence for Companies Hiring AI PMs & Heads of AI

Here is the exact sequence I’ve used (and tweaked over dozens of campaigns) when selling an AI talent solution to companies with an open AI leadership role. The examples below pitch a fictional “AI hiring platform,” but you can swap the value prop to your own — the framing, pain points, and curiosity angles are what matter.

Sequence settings (in the sequencer):

  • Touch 1: Send immediately after launch
  • Touch 2: 3 days after Touch 1 (skip Saturday/Sunday)
  • Touch 3: 4 days after Touch 2 (skip weekends)
  • Auto‑unenroll: If a lead replies, stop the sequence.

Touch 1 — Day 1: Direct, problem‑aware, no fluff

Subject: Your AI PM opening
Preview text: a faster way to fill it

Hi ,

I saw the AI Product Manager role you’re hiring for at . Finding someone who can bridge product strategy and LLM-native architecture is brutal right now — most traditional searches take 90+ days and still miss on quality.

We built [Your Solution] to surface pre‑vetted AI product leaders matched to your exact tech stack and stage, typically in under two weeks.

Worth 15 minutes to see how it works?

Best,

Why this works: It names the specific pain (90‑day searches for a hybrid role) and offers a concrete, time‑bound alternative without jargon. The ask is light — a 15‑minute look, not a commitment.


Touch 2 — Day 3: Different angle, social proof

Subject: How Acme hired their Head of AI in 11 days
Preview text: (no hard pitch, just a story)

Hey ,

Quick follow‑up — I thought you’d find this relevant.

One of our clients, a Series B infrastructure startup, had the same Head of AI gap last quarter. Their CTO told us the role stayed open for 120 days before we got involved. After they used our matching flow, they interviewed four strong candidates in the first week and made an offer on Day 11.

No aggressive outreach, just a smarter pipeline. Happy to share how we’d tailor that for .

Why this works: Instead of a “just checking in” follow‑up, it introduces a specific, comparable success story. The reader sees a peer in a similar situation — that’s way stronger than repeating the original pitch.


Touch 3 — Day 7: Breakup email, curiosity with a door left open

Subject: Should I take the hint?
Preview text: one last thought on the AI PM role

,

I’ll leave this here — if the timing isn’t right, no worries.

One thing I’d hate for you to overlook: the pool of AI product leaders who understand both shipping velocity and model evaluation is tiny. The companies that move first — even if it’s just an exploratory conversation — tend to lock in the best talent.

If you ever want to see what that pipeline would look like at , the door is open.

Why this works: It doesn’t beg or insult. It respects their silence, plants a scarcity seed, and makes it easy for them to come back later without admitting they ignored two previous emails.


Personalization note: When you use Origami’s AI‑written option, the system will inject deeper specifics — like a recent funding round the company raised or an AI product launch — directly into the message. The templates above give you a strong base; letting the agent layer in that real‑time data can push reply rates even higher.


Step 4 — Send the Sequence Directly from Origami

Once the sequence is loaded in the sequencer, you launch it without ever leaving Origami. That’s the part that changes your workflow: list‑building, enrichment, and multi‑stage outreach all happen under one roof.

How sending works

  • The sequencer is included on all paid plans. You’re only paying for the credits used to enrich leads — the actual email sending costs nothing extra.
  • Each touch fires automatically with the delays you set.
  • Opens, clicks, and replies flow back into the same dashboard where you built the list, so you’re not toggling between tabs.

Tracking and prospect context

When you click into a contact, you see the full activity log — opened the first email, clicked on Day 3, never replied — alongside their enriched profile (title, company, tech tools, the exact job posting you originally sourced). That context is gold: it reminds you exactly why you reached out and lets you personalize any manual follow‑up.

Automatic un‑enrollment saves you from embarrassment

The moment someone replies, Origami pulls them out of the sequence. You’ll never send a “Should I take the hint?” breakup email right after they book a meeting. If they reply with a “not interested,” you can manually re‑enroll them later or archive them.

What response rate to expect for this audience

Targeting companies actively hiring AI product leaders with a tight, 50‑70‑contact qualified list, you should see:

  • Open rates: 55–75% (these are timely, role‑specific subjects to a known need)
  • Reply rates: 8–15% across the whole campaign (not just first touch). The majority of replies come after Touch 2 or 3, which is why the follow‑up sequence is critical.
  • Meeting‑booked rate: Often 3–7% of the list – but because each company represents a potentially large deal, even 2–3 meetings can produce significant pipeline.

These numbers assume you’ve done the refinement in Step 2. If your reply rate is below 5%, revisit the list quality before touching the messaging.

When to iterate on messaging vs. the list

After the first 50 contacts, look at the data:

  • High opens, low replies → Your subject lines grab attention, but the body doesn’t resonate. Try a different pain point or add a real case study.
  • Low opens, low replies → Your list probably hasn’t been refined enough. Re‑filter for recent postings and decision‑maker contacts.
  • Replies that say “role already filled” → Your enrichment data (job posting age) missed a close. Tighten the freshness filter.
  • Strong reply rates and meetings → Scale up the qualified list using the same prompt criteria.

The sequencer’s built‑in analytics make this diagnosis straightforward — you won’t need a separate analytics tool.


Frequently Asked Questions